In 2006, the most active sectors for affiliate marketing were the adult gambling, retail industries and file-sharing services.[17]:149–150 The three sectors expected to experience the greatest growth are the mobile phone, finance, and travel sectors.[17] Soon after these sectors came the entertainment (particularly gaming) and Internet-related services (particularly broadband) sectors. Also several of the affiliate solution providers expect to see increased interest from business-to-business marketers and advertisers in using affiliate marketing as part of their mix.[17]:149–150
→Developer Tools [2]→Drivers [2]→Education [5]→Email [4]→Foreign Exchange Inv... [15]→General [7]→Graphic Design [8]→Hosting [3]→Internet Tools [14]→Mp3 & Audio [5]→Networking [1]→Other Investment Sof... [3]→Personal Finance [2]→Productivity [23]→Registry Cleaners [7]→Reverse Phone Lookup [2]→Security [7]→System Optimization [9]→Utilities [6]→Video [4]→Web Design [7]
As of 2014, ClickBank has more than six-million clients and distributes in 190 countries and has carved out a niche in being an easy-to-use platform for entrepreneurs and businesses, enabling powerful online and mobile commerce across a wide variety of lifestyle categories.[6] In August 2014, ClickBank handled approximately 30,000 transactions daily.[2]
Another thing to consider is that even if you break even on the first sale, you're still winning. All you need to do is create more content about other problems that target market may have following the same principle and queue them one after the other. For example if we target women that want to lose weight they may also have wrinkle problems, digestion problems, diabetes, aging problems etc. We can easily create a chain of issues we run the email list through, let them opt in for what matches their issues and make several sales to that audience.

When promoting affiliate offers, just make sure you are fully aware of all the terms and conditions attached to your affiliate program. Some programs can be strict about how they allow you to promote their products. For example, some may limit you to banner ads and links only, while others will allow you to use paid advertising, but won't allow email marketing. 

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